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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Nanomedicine. 2015 Jan 31;11(5):1277–1283. doi: 10.1016/j.nano.2014.12.016

Figure 2.

Figure 2

Kinetics of cellular internalization of gold nanoparticles: (A) Transmission electron microscopy images of PC3 cells treated with goserelin-conjugated gold nanorods (gAuNRs) and pegylated gold nanorods (pAuNR) for different times of incubation between 15 min and 72 h, demonstrating cell-surface binding, internalization, entrapment within endosomes, and persistence within cells even beyond 24 h. Arrows point to AuNRs. Note greater accumulation of AuNRs intracellular in the gAuNR group compared to the pAuNR group. (B) Quantitative analysis of cellular uptake by ion coupled plasma mass-spectroscopy.