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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Insect Biochem Mol Biol. 2014 Dec 29;62:75–85. doi: 10.1016/j.ibmb.2014.12.006

Table 1.

Functions of some immulectins in lepidopteran insects

Name inducibility tissue agglutination Ca2+-depen
dence
binding proPO
activation
melanization encapsulation reference
H F
M. sexta
IML-1
Ec, Ml, Sc no yes Ec, Sa, Sc yes - yes no yes Yu et al., 1999
M. sexta
IML-2
Ec, Ml, Sc no yes Ec yes/no* lipid A, LPS, PG,
LTA, mannan,
laminarin
yes yes yes Shi and Yu, 2012;
Yu and Kanost, 2000,
2003, 2004;
M. sexta
IML-3
Ec, Ml, Sc no yes Ec yes LPS, LTA,
laminarin
- no yes Yu et al., 2005;
Ling et al., 2008;
M. sexta
IML-4
Ec, Ml, Sc no yes Ec, Sa, Sc yes/no* LPS, LTA,
laminarin
yes yes yes Yu et al., 2006
H. armigera
CTL1~8
Bt, Sa, Pp,
NPV, 20E
yes yes Ec, Sa (1,3);
Ca (1);
- (2, 3~8)
- - - - - Chai et al., 2008;
Wang et al., 2012
H. cunea
Hdd15
Ec, Ml - yes - - LPS - - - Shin et al., 2000;
B. mori LBP,
MBP, etc.
Ec, Ml, Sc yes yes Ec, Smi
(LBP);
Sma, Ml, Sc
(MBP)
- (LBP);
+ (MBP)
lipid A (LBP);
TA, mannan, PG
(MBP)
- yes (LBP) - Koizumi et al., 1997,
1999;
Watanabe et al., 2006;
Tanaka et al., 2008;

Bt, Bacilus thuringiensis Ml, Micrococcus luteus; Sa, Staphylococcus aureus; Ec, Escherichia coli; Sma, Serratia marcescens; Smi, Salmonella minnesota, Sc, Saccharomyces cerevisiae; Ca, Candida albicans; Pp, Pichia pastoris; NPV, nucleopolyhedrovirus; 20E, 20-hydroxyecdysone; H: hemocytes; F: fat body; PG, peptidoglycan; LPS, lipopolysaccharide; LTA, lipoteichoic acid; TA, teichoic acid;

*

: Ca2+ required for agglutination of E. coli, but not for binding to microbial components.