a. An illustration of a double-stranded DNA molecule passing through a solid-state nanopore. Inset, a TEM image of a silicon nitride nanopore. b. Current signals from translocations through SiNx nanopores can be as large as several nanoamperes. c. Nanopore current blockades are sensitive to the orientation and position of a translocating molecule. d. Simplified electrical equivalent circuit of a solid-state nanopore, highlighting the access resistance RA and the membrane capacitance CM.
Images a+b are from 28, with permission.
Images c+d are from 45, with permission.