Table 1.

Testing each predictor against disease status

Predictor	OR	95% CI	P-value
Cerebral atrophy	25.65	6.08 – 108.24	<0.0001
Brain stem atrophy or hypoplasia	25.67	4.96 – 132.94	<0.0001
Cerebral WM loss/ventricular dilation	36.67	4.37 – 307.92	0.001
Irregular high signal T2 in cerebral subcortical region	13.56	1.53– 120.03	0.019
Anterior >Posterior gradient on T1 or T2	7.92	2.29 – 27.40	0.001
Low signal T2 in WM	0.25	0.08 – 0.78	0.019
Calcification on MR	19.44	4.91 – 76.93	<0.0001
Cerebellar WM abnormal	1.66	0.56 – 4.96	0.364
Basal ganglia signal abnormal	1.47	0.50 – 4.33	0.481
Basal ganglia atrophy	6.42	1.70 – 24.24	0.006
Corpus callosum thin	5.50	0.61 – 49.37	0.128
Cysts, non temporal	3.27	1.01 – 10.56	0.047
Temporal horn dilation	14.73	3.88 – 55.99	<0.0001
Frontal gyri swelling	2.08	0.70 – 6.23	0.190
Frontal atrophy	11.54	2.21 – 60.19	0.004
Swollen temporal pole	5.26	1.56 – 17.76	0.007
Temporal atrophy	33.82	3.93 – 291.15	0.001
Mid parietal swollen gyri	1.93	0.61 – 6.14	0.266

^*WM, white matter