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. 2015 Apr 22;17(4):930–938. doi: 10.1208/s12248-015-9770-4

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© The Author(s) 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Perl’s Prussian blue staining on liver and spleen sections of rats dosed with ABT-207 or h5F9-AM8. In animals treated with ABT-207, liver iron deposition (a) was visible between week 1 and week 9 and iron reduction (b) in the spleen could be seen within this time frame. In animals treated with h5F9-AM8 (c, d), this observation is more pronounced. Bar represents 3 mm for all panels