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. 2015 Jun 23;6:186. doi: 10.3389/fphys.2015.00186

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Copyright © 2015 Maneta, Warren, Hay and Khan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IL-1β release from maternal blood mononuclear cells (MBMCs). (A) Coincubation with LPS and BzATP elicited greater production of IL-1β from MBMCs. P4, prolactin, the NFkB inhibitor QNZ and the caspase-1 inhibitor YVAD-CHO all inhibited IL-1β release. (B) Western blotting showed positive expression for the P4 receptor in choriodecidua (CD; n = 6), some expression in PLBMCs (n = 6) but undetectable levels in CBMCs (n = 6). ^*P < 0.05 when compared using Dunnett's test.