Table 2.
Patient characteristics for patients treated with standard RT or esophagus and contralateral lung-sparing IMRT.
| Normal tissue-sparing IMRT (n = 44) | Standard (n = 38) | p | |
|---|---|---|---|
| Age (years) | |||
| Median | 72 | 67 | 0.63 |
| Range | 30–87 | 48–83 | |
| Gender | |||
| Male | 25 (56%) | 17 (45%) | 0.28 |
| Female | 19 (44%) | 21 (55%) | |
| Histology | |||
| Adenocarcinoma | 18 (41%) | 14 (37%) | 0.29 |
| Squamous cell carcinoma | 15 (34%) | 12 (32%) | |
| Small cell carcinoma | 7 (16%) | 10 (26%) | |
| Non-small cell lung cancer, NOS | 4 (9%) | 2 (5%) | |
| Smoking (pack years) | |||
| Never | 3 (7%) | 1 (3%) | 0.38 |
| 1–20 | 5 (11%) | 13 (34%) | |
| 21–40 | 14 (37%) | 5 (13%) | |
| >40 | 22 (50%) | 18 (47%) | |
| Race | |||
| White | 39 (89%) | 29 (76%) | 0.15 |
| Non-white | 5 (11%) | 9 (24%) | |
| Clinical stage | |||
| II | 7 (16%) | 4 (11%) | 0.64 |
| IIIA | 14 (32%) | 19 (50%) | |
| IIIB | 16 (36%) | 11 (29%) | |
| IV | 7 (16%) | 4 (11%) | |
| Recurrent | |||
| No | 37 (84%) | 34 (89%) | 0.48 |
| Yes | 7 (16%) | 4 (11%) | |
| ECOG performance status | |||
| 0–1 | 27 (61%) | 30 (79%) | 0.12 |
| 2 | 12 (27%) | 5 (13%) | |
| 3 | 5 (11%) | 3 (8%) | |
| Weight loss | |||
| <10% | 39 (89%) | 34 (89%) | 0.70 |
| >10% | 5 (11%) | 4 (11%) | |
| Location | |||
| Right upper | 16 (36%) | 10 (26%) | 0.10 (upper vs. lower) |
| Right middle | 5 (11%) | 3 (8%) | |
| Right lower | 9 (20%) | 3 (8%) | |
| Left upper | 9 (20%) | 16 (42%) | |
| Left lower | 4 (9%) | 5 (13%) | |
| Lymph node only | 1 (2%) | 1 (3%) | |