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. 2015 Jun 23;9:158. doi: 10.3389/fnbeh.2015.00158

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Copyright © 2015 Chew, Ryu, Ng, Ma, Dasgupta, Neo, Zhao, Zhong, Bichler, Sajikumar and Goh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Knocking down of GSK3β does not affect spatial memory in Morris water maze. (A) Graph shows average time needed for both shCon or shGSK3β lentivirus-injected mice to find hidden platform for each day of training (with four trials per day pooled). (B) Graph shows average distance swum by each group of mice to find hidden platform for each day of training. (C) Graph shows time spent exploring each quadrant during the probe trial (shCon: n = 11 shGSK3: n = 10, *p < 0.05, ***p < 0.001, error bars are SEM, ANOVA followed by Bonferroni Post hoc comparisons). (D) Graphs shows number of entries into platform area by both groups of mice during the probe trial.