. Author manuscript; available in PMC: 2015 Jun 23.

Published in final edited form as: Tuberculosis (Edinb). 2007 Dec 18;88(3):187–196. doi: 10.1016/j.tube.2007.10.006

Table II.

Disease parameters associated to Mtb H37Rv aerosol infection of rabbits after intramuscular dexamethasone treatment from weeks 10 to 15.

No. Weeks after aerosol	No. of rabbits	No. of tubercles	Tubercle diameter (mm)	Lung weight (g)	Right upper lobe CFU (median [range])	No. rabbits culture-negative at any site
Higher-Dose Aerosol
Week 15	6	9 ± 4	0.7 ± 0.3	12.0 ± 0.5	4050 [0-23,000]	2/6
					P=0.13^*
Week 20	6	14 ± 5	1.7 ± 0.7	13.0 ± 0.7	1356 [375-71,000]	0/6
					P=0.002^*

Lower-Dose Aerosol
Week 15	3	30 ± 23	1.2 ± 0.3	12.2 ± 0.3	0 [0-8850]	2/3
Week 25	18	7 ± 5	0.7 ± 0.3	12.2 ± 0.4	50 [0-6000]^**	3/18

P values compared to 5 week values except for those denoted with an asterisk which are compared to the untreated control at the same time point

^**

No P value could be calculated since all RUL homogenates in the control group were culture-negative