Table 2.
Leptin levels (ng/mL), sOB-R (ng/mL), and LFI among PCOS subjects and in the presence/absence of overweight/obesity.
| PCOS [n = 18] | Control [n = 60] | p | |
|---|---|---|---|
| Leptin (ng/mL) | 44.29 (16.14–47.78) | 15.16 (11.87–36.27) | 0.013 |
| sOB-R (ng/mL) | 14.80 (11.11–17.20) | 20.06 (14.75–31.85) | 0.002 |
| FLI | 2.81 (1.12–3.59) | 0.86 (0.44–2.16) | 0.001 |
| BMI kg/m2 | 24.36 (4.88) | 22.88 (4.48) | 0.234 |
|
| |||
| Lean (+PCOS) [n = 10] | OW/OB (+PCOS) [n = 8] | p | |
|
| |||
| Leptin (ng/mL) | 16.97 (10.60–45.55) | 45.67 (41.98–48.04) | 0.013 |
| sOB-R (ng/mL) | 16.62 (11.61–17.96) | 11.47 (7.59–16.44) | 0.042 |
| FLI | 1.21 (0.54–2.89) | 3.33 (2.82–6.12) | 0.000 |
|
| |||
| Lean (+PCOS) (n = 10) | Lean (−PCOS) [n = 46] | p | |
|
| |||
| Leptin (ng/mL) | 16.97 (10.60–45.55) | 14.32 (10.52–24.93) | 0.282 |
| sOB-R (ng/mL) | 16.62 (11.61–17.96) | 23.69 (17.49–36.76) | 0.002 |
| FLI | 1.21 (0.54–2.89) | 0.68 (0.37–1.171) | 0.041 |
|
| |||
| OW/OB (+PCOS) [n = 8] | OW/OB (−PCOS) [n = 14] | p | |
|
| |||
| Leptin (ng/mL) | 45.67 (41.98–48.17) | 39.18 (20.53–44.77) | 0.029 |
| sOB-R (ng/mL) | 11.47 (7.59–16.44) | 12.02 (9.09–15.26) | 0.768 |
| FLI | 3.33 (2.82–6.12) | 2.94 (1.88–4.43) | 0.172 |
Data are presented by median and interquartile (IQ) values (25%–76%) and BMI as mean and SD. Data were analyzed by nonparametric Wilcoxon/Kruskal-Wallis test. Two-tailed p value less than 0.05 (<0.05) is significant.