Table 2.
Expression profile data for miR-125b and miR-34a in cervical lesions.
| miR-125b | miR-34a | |||||
|---|---|---|---|---|---|---|
| ΔCt ± sd | 2−ΔΔCt | t-test | ΔCt ± sd | 2−ΔΔCt | t-test | |
| Normal (HPV−) (n = 29) | −6.51 ± 1.73 | Reference | −0.80 ± 1.16 | Reference | ||
| Normal (HPV+) (n = 20) | −7.59 ± 1.77 | 2.11 (0.64–7.01) | 0.038 | −1.56 ± 1.47 | 1.69 (0.76–3.78) | 0.049 |
| LSIL (n = 28) | −6.09 ± 1.44 | 0.75 (0.23–2.48) | 0.320 | −0.82 ± 1.81 | 1.01 (0.45–2.27) | 0.955 |
| HSIL (n = 29) | −5.65 ± 2.15 | 0.55 (0.17–1.83) | 0.099 | −0.94 ± 1.59 | 1.10 (0.49–2.46) | 0.707 |
| ICC (n = 8) | −4.24 ± 2.10 | 0.21 (0.06–0.69) | 0.004 | −1.86 ± 1.56 | 2.08 (0.93–4.66) | 0.042 |
Ct: cycle threshold; Sd: standard deviation; LSIL: low-grade squamous intraepithelial lesions; HSIL: high-grade squamous intraepithelial lesions; ICC: invasive cervical carcinoma.