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. 2015 Jun 23;5:11511. doi: 10.1038/srep11511

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Copyright © 2015, Macmillan Publishers Limited

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Positive correlations between Th17 levels and polyclonal T-cell effector subsets found within PHI cohort: % of Th17 cells versus (vs.) Th1 (CD4⁺IFN-γ⁺) counts (A) and % of Tc17 (CD8⁺IL-17⁺) cells (B) both at baseline; % of Th17 cells vs. % of Th1 cells (C) and % of Tc1 (CD8⁺IFN-γ⁺) cells (D) both at one year p.i. Polyclonal T-cell effector sub-populations were determined by flow cytometry after 6 hours of stimulation with a mixture of anti-CD3/anti-CD28 antibodies as described in Materials and Methods. Symbols distinguish individual patients from the different sub-groups indicated in the figure. PHI: primary HIV infection cohort. TPs: typical progressors. RPs: rapid progressors. All r and p values correspond to Spearman’s correlations.