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Effect of 24-hour incubation with 7 (control) or 30 mM (HG) glucose on the NAD+ level of HUVECs with or without coincubation with flavonoids. Data are expressed as mean ± standard error from four independent experiments. ∗ P < 0.05 compared to control; ∗∗ P < 0.05 compared to incubation with high glucose alone; ## P < 0.1 compared to incubation with high glucose alone.
