Table 2.
Comparison of percentages of different types of aneuplodies detected by NGS and aCGH screening of the same WGA products in Phase I study
| Parameters | NGS | aCGH | p |
|---|---|---|---|
| Total number of WGA products analyzed | 164 | 164 | |
| Euploid % (n) | 37.2 % (61) | 37.2 % (61) | 1.000a |
| Aneuploid % (n) | 62.8 % (103) | 62.8 % (103) | 1.000a |
| Monosomy % (n) | 19.4 % (20) | 19.4 % (20) | 1.000a |
| Trisomy % (n) | 16.5 % (17) | 16.5 % (17) | 1.000a |
| Dual chromosomal abnormality % (n) | 24.3 % (25) | 24.3 % (25) | 1.000a |
| Complex chromosomal abnormality % (n) | 35.9 % (37) | 37.8 % (39) | 0.885a |
| Mosaicism % (n) | 2.5 % (4) | 1.2 % (2) | 0.683b |
aby Chi-square analysis
bby Fisher’s exact test