Table 2.
Gene | Fold change | ||||
---|---|---|---|---|---|
Symbol | Description | Luminal A | Luminal B | Triple negative | |
1 | GRIA4 | Glutamate receptor, ionotropic, AMPA 4 | −36.73 | −10.59 | −22.19 |
2 | PIGR | Polymeric immunoglobulin receptor | −89.25 | −24.54 | −55.02 |
3 | TUBB3 | Tubulin, beta 3 class III | 11.60 | 13.94 | 22.60 |
4 | SLC26A3 | Solute carrier family 26 (anion exchanger), member 3 | −11.33 | −10.86 | −16.08 |
5 | LINC00844 | Long intergenic non-protein coding RNA 844 | −15.33 | −25.99 | −13.74 |
6 | FIGF | c-Fos induced growth factor | −49.22 | −37.19 | −18.18 |
7 | SMYD1 | SET and MYND domain containing 1 | −31.85 | −12.84 | −17.43 |
8 | CXCL2 | Chemokine (C-X-C motif) ligand 2 | −30.24 | −13.34 | −16.54 |
9 | ALB | Albumin | −76.81 | −54.76 | −109.05 |
10 | DRD2 | Dopamine receptor D2 | −19.79 | −15.78 | −10.30 |
11 | DLK1 | Delta-like 1 homolog | −82.62 | −47.07 | −19.17 |
12 | RNF186 | Ring finger protein 186 | −64.51 | −23.30 | −61.59 |
13 | C2orf40 | Chromosome 2 open reading frame 40 | −69.81 | −13.55 | −18.39 |
14 | OXTR | Oxytocin receptor | −48.00 | −24.36 | −28.75 |
15 | DAPL1 | Death associated protein-like 1 | −20.83 | −20.53 | −25.10 |
16 | COL10A1 | Collagen, type X, alpha 1 | 36.84 | 13.82 | 39.31 |
17 | FGFBP1 | Fibroblast growth factor binding protein 1 | −50.79 | −50.39 | −17.39 |
18 | NTRK2 | Neurotrophic tyrosine kinase, receptor, type 2 | −23.96 | −15.75 | −48.94 |
19 | SCARA5 | Scavenger receptor class A, member 5 | −21.61 | −19.18 | −39.67 |
20 | DLK2 | Delta-like 2 homolog | −28.32 | −11.49 | −15.35 |
21 | AFP | Alpha-fetoprotein | −29.03 | −14.92 | −42.89 |
22 | HPSE2 | Heparanase 2 | −29.29 | −20.28 | −15.26 |
23 | CAPN6 | Calpain 6 | −28.50 | −38.50 | −13.62 |
24 | LINC00640 | Long intergenic non-protein coding RNA 640 | −18.13 | −22.01 | −12.84 |
25 | LRRC3B | Leucine rich repeat containing 3B | −13.77 | −21.02 | −13.11 |
26 | IL22RA2 | Interleukin 22 receptor, alpha 2 | −12.01 | −22.72 | −14.56 |
27 | KCNJ16 | Potassium inwardly-rectifying channel, subfamily J, member 16 | −35.51 | −11.58 | −17.09 |
28 | MMP11 | Matrix metallopeptidase 11 | 24.75 | 12.45 | 50.25 |
aGenes with corrected p-value < 0.05 and fold changes ≥ 10 in all the 3 subtypes using GeneSpring 12.6 software