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Experimental protocols, clamped glucose, and insulin levels during hyperinsulinemic-euglycemic and hyperinsulinemic-hypoglycemic clamps in healthy subjects. Values are mean ± SE. Endothelial function measurements: 0.4 mg nitroglycerin plus two-dimensional images of the brachial artery and pulsed Doppler flow-mediated dilation. Arterialized blood was obtained via the heated hand vein technique. hrs, hours.
