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. 2015 Feb 9;64(7):2457–2466. doi: 10.2337/db14-1364

Figure 3.

Figure 3

i3vt DET and NPH insulin reduce food intake and body weight in rats. i3vt DET and NPH insulin each reduced food intake over a 24-h period (A) relative to control (CON). After 48 h, intake by the DET group remained reduced, whereas that of the NPH group had returned to CON levels (B). Both NPH insulin and DET rats lost weight in the 24-h postinfusion (C); however, only the DET group maintained the weight loss after 48 h (D). Data are means ± SEM. *P < 0.05 vs. control, +P < 0.05 vs. NPH insulin.