Table 2.
Salt bridge formations between IκBα and the p50/RelA subunits of NF-κB.
| IκBα | RelA | IκBα | p50 | RelA | p50 |
|---|---|---|---|---|---|
| SALT BRIDGES | |||||
| GLU85 | ARG302 | GLU41 | LYS354 | ARG198 | ASP302 |
| GLU85 | LYS301 | GLU72 | LYS352 | ARG198 | GLU265 |
| GLU86 | ARG302 | GLU72 | LYS354 | ARG201 | ASP254 |
| GLU125 | ARG302 | ASP73 | LYS354 | ARG201 | GLU265 |
| ARG143 | ASP294 | GLU138 | LYS323 | GLU211 | ARG252 |
| GLU153 | ARG295 | ARG143 | GLU350 | ASP217 | ARG305 |
| GLU153 | ARG297 | GLU286 | ARG305 | ASP243 | ARG252 |
| ARG218 | ASP243 | GLU286 | LYS272 | ARG246 | ASP271 |
| ARG218 | GLU211 | GLU287 | LYS272 | ||
| ASP226 | ARG253 | ASP290 | LYS272 | ||
| ARG264 | GLU22 | GLU292 | LYS249 | ||
| GLU282 | ARG30 | GLU292 | LYS272 | ||
| GLU282 | ARG158 | ||||
| GLU282 | LYS79 | ||||
| GLU284 | ARG246 | ||||
| GLU284 | LYS79 | ||||
| ASP285 | LYS218 | ||||
| GLU286 | LYS218 | ||||
| GLU287 | ARG246 | ||||
| GLU287 | LYS218 | ||||
| ASP290 | LYS221 | ||||
| GLU292 | ARG246 | ||||
Residues found in interactions in the crystal structure 1IKN are shown in bold. All salt bridges occur in at least 2 of the replicate simulations throughout the whole simulation.