Fig. 5.

Time courses of coagulation markers during surgery in the representative case of each group. a: valve surgery; b: aortic replacement surgery. ■ (closed column): thrombin–antithrombin complex (ng/mL); □ (open column): soluble fibrin monomer complex (μg/mL). CPB time is shown by the gray zone. (1) and (7): pre-operation; (2) and (8): pre-CPB; (3) and (9): the start of CPB; (4) and (10): 1 h after the start of CPB; (5) and (13): the end of CPB; (6) and (15): post-operation; (11): 2 h after the start of CPB; (12): 3 h after the start of CPB; (14): 1 h after the end of CPB