Table 1.
Characteristics of Jackson Heart Study participants with and without chronic kidney disease
| No CKD | CKD | p-value | |
|---|---|---|---|
| (n = 849) | (n = 173) | ||
| Age, years | 58.9 (0.4) | 60.8 (0.9) | 0.041 |
| Female gender, % | 68.3 | 65.1 | 0.452 |
| Less than high school education, % | 18.1 | 26.7 | 0.022 |
| Low income, % | 10.8 | 15.6 | 0.142 |
| Diabetes, % | 21.2 | 40.6 | <0.001 |
| History of stroke, % | 2.9 | 8.8 | 0.002 |
| History of myocardial infarction, % | 4.1 | 7.5 | 0.074 |
| Current smoking, % | 5.3 | 7.4 | 0.329 |
| Waist circumference, cm | 99.1 (0.5) | 104.5 (1.3) | <0.001 |
| Total cholesterol, mg/dL | 200.7 (1.4) | 205.0 (3.5) | 0.242 |
| HDL-cholesterol, mg/dL | 54.1 (0.5) | 51.5 (1.0) | 0.043 |
| C-reactive protein > 3 mg/L, % | 46.7 | 52.1 | 0.213 |
| Mean clinic SBP, mmHg | 126.0 (0.6) | 132.9 (1.6) | <0.001 |
| Mean clinic DBP, mmHg | 77.3 (0.4) | 77.1 (0.9) | 0.781 |
| Mean 24-h SBP, mmHg | 125.0 (0.4) | 132.7 (1.4) | <0.001 |
| Mean 24-h DBP, mmHg | 73.8 (0.3) | 76.2 (0.9) | 0.004 |
| eGFR, mL/min/1.73 m2 | 94.4 (0.6) | 77.7 (2.4) | <0.001 |
| Albumin-to-creatinine ratio, mg/g | 5.5 (3.7, 9.4) | 55.3 (22.9, 125.5) | <0.001 |
| Antihypertensive medication use, % | |||
| Aldosterone antagonist | 1.6 | 4.9 | 0.073 |
| Alpha blocker | 11.6 | 16.9 | 0.152 |
| ACE inhibitor | 35.8 | 47.0 | 0.035 |
| Angiotensin II receptor blocker | 12.2 | 13.3 | 0.753 |
| Beta blocker | 24.1 | 18.6 | 0.234 |
| Calcium channel blocker | 32.6 | 47.2 | 0.008 |
| Diuretic | 65.6 | 65.4 | 0.971 |
| Renin inhibitor | NA | NA | --- |
| Vasodilator | 0.8 | 1.0 | 0.839 |
CKD chronic kidney disease, defined as an estimated glomerular filtration rate < 60 mL/min/1.73 m2 or an albumin-to-creatinine ratio ≥ 30 mg/g; HDL high-density lipoprotein, SBP systolic blood pressure, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, ACE angiotensin converting enzyme
Numbers in table are presented as mean (standard error) or percent except albumin-to-creatinine ratio, which is presented as median (interquartile range)