Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 May 4;43(11):5297–5306. doi: 10.1093/nar/gkv438

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Figure 6. — (A) Autoradiograms of DNase I footprint of 5’ end labelled top (left) or bottom (right) strand of the GFG/CTC duplex containing an AP site in the presence of increasing concentrations of Λ-[Fe₂L^1a₃]Cl₄ (lanes 1–4) and Δ-[Fe₂L^1a₃]Cl₄ (lanes 5–8). Lane C; GFG/CTC duplex in the absence of flexicates. Lanes 1–4; GFG/CTC duplex mixed with Λ-[Fe₂L^1a₃]Cl₄ at 0.5:1, 1:1, 2:1 and 3:1 (flexicate:DNA duplex) ratios, respectively. Lanes 5–8; DNA duplex mixed with Δ-[Fe₂L^1a₃]Cl₄ at 0.5:1, 1:1, 2:1 and 3:1 (flexicate:DNA duplex) ratios, respectively. Lane C0; DNA duplex in the absence of flexicates and DNase I. Lanes T, G and G + A correspond to T, G and G + A ladders. The nucleotide sequence of the oligonucleotide is shown on the left side of the gels. (B) Sequence of the DNA duplex containing an AP site indicated by letter ‘F’ showing sites (shown by circles) protected by Λ- and Δ-[Fe₂L^1a₃]Cl₄ from the cleavage by DNase I.