Mean change in gain, before versus after intratympanic gentamicin (ITG) treatment, for ipsilateral horizontal canal (IHC), ipsilateral anterior canal (IAC), and ipsilateral posterior canal (IPC). Error bars denote 1 SD; p values denote significance of difference in mean change in gain, before versus after ITG treatment, between multiple- and single-treatment groups (Mann-Whitney test). Data from subject S5 were not used in analysis, because pretreatment data were not available.