SUMMARY OF MEAN AVOR GAINS AND CLINICAL DATA BEFORE AND AFTER INTRATYMPANIC GENTAMICIN TREATMENT

Subject	IHC Gain	IAC Gain	IPC Gain	Clinical HTT Signa	% Caloric Asymmetryb	No. of Vertigo Attacksc	Additional Injectionsd
S1	0.84/0.34	0.78/0.42	0.57/0.42	−/+	9/0	12/1
S2	1.11/0.53	0.89/0.26	0.92/0.21	−/+	25/88	78/0
S3	0.86/0.45	0.89/0.47	0.74/0.35	−/+	4/3	10/0
S4	0.86/0.39	0.99/0.37	0.82/0.30	−/+	23/92	70/3
S5	ND/0.27	ND/0.29	ND/0.18	−/+	52/100e	3/0
S6	0.73/0.32	0.70/0.28	0.82/0.48	−/+	15/42	20/0
S7	0.58/0.31	0.34/0.37	0.99/0.32	+/+	100/100	52/0
S8	1.31/0.38	0.80/0.30	0.88/0.29	−/+	32/31	39/0
S9	0.94/0.20	0.96/0.39	0.91/0.21	−/+	33/82	52/0
S10	0.74/0.74	0.63/0.70	0.62/0.68	+/+	17/22	15/0
S11	1.04/0.61	0.85/0.56	0.77/0.67	−/+	8/11	12/0
M1	0.90/0.75	0.48/0.36	0.65/0.41	−/+	24/100e	6/0	7
M2	0.88/0.57	0.69/0.57	0.65/0.40	−/−	17/18	45/4	3, 5, 7, 11
M3	0.84/0.90	0.93/0.83	0.89/0.88	−/−	1/1	15/2	12
M4	1.00/0.30	1.05/0.44	0.74/0.31	−/+	6/ND	11/4	5
M5	0.76/0.50	0.83/0.53	0.72/0.31	+/+	16/44	7/3	4
M6	0.59/0.77	0.63/0.61	0.77/0.87	−/+	37/ND	21/3	3, 5
M7	0.82/1.26	0.87/0.66	0.57/0.50	−/+	4/18	12/22	7, 9

Data before slash are pretreatment; those after slash are posttreatment.

aVOR — angular vestibulo-ocular reflex; S — single-treatment group; M — multiple-treatment group: IHC — ipsilateral horizontal canal; IAC — ipsilateral anterior canal; IPC — ipsilateral posterior canal; HTT — head thrust test; ND — not done.

^aPlus sign indicates appearance of relaxation saccade on HTT, suggesting to clinical examiner deficit in horizontal aVOR; minus sign indicates no refixation saccade, indicating clinically normal horizontal aVOR.

^bUnilateral vestibular weakness calculated by formula of Jongkees et al.¹⁴

^cData are 6 months pretreatment (before slash) and either 6 months posttreatment or until second treatment (after slash).

^dData are number of months after initial treatment until subjects received additional treatments.

^eSubject had no response to ice-water irrigation.