Table 3.
Operative findings of subjects who underwent curative surgical resection of pancreatic cancer based on DM status.
| Variable | DM (N=275) | Non-DM (N=213) | Total (N=488) | p-value* |
|---|---|---|---|---|
| Site of Pancreatic Mass | 0.063 | |||
| Head/uncinate | 222 (81.6%) | 146 (71.2%) | 368 (77.1%) | |
| head and body | 12 (4.4%) | 9 (4.4%) | 21 (4.4%) | |
| body | 12 (4.4%) | 14 (6.8%) | 26 (5.5%) | |
| body and tail | 5 (1.8%) | 9 (4.4%) | 14 (2.9%) | |
| tail | 21 (7.7%) | 27 (13.2%) | 48 (10.1%) | |
| Operation Type | 0.005 | |||
| Pancreaticoduodenectomy | 222 (80.7%) | 160 (75.1%) | 382 (78.3%) | |
| Distal pancreatectomy | 36 (13.1%) | 48 (22.5%) | 84 (17.2%) | |
| Total pancreatectomy | 17 (6.2%) | 5 (2.3%) | 22 (4.5%) | |
| Portal or Superior Mesenteric Vein Reconstruction | 0.208 | |||
| Yes | 49 (18.8%) | 24 (14.1%) | 73 (16.9%) | |
| Resection Status | 0.829 | |||
| R0 (negative margins) | 221 (81.0%) | 166 (80.2%) | 387 (80.6%) | |
| R1 (microscopically positive margins) | 42 (15.4%) | 34 (16.4%) | 76 (15.8%) | |
| R2 (grossly positive margins) | 5 (1.8%) | 2 (1.0%) | 7 (1.5%) | |
| Maximum tumor dimension (cm) | 0.002 | |||
| Mean (SD) | 3.59 (1.42) | 3.27 (1.69) | 3.45 (1.55) | |
| Tumor Grade | 0.012 | |||
| Well differentiated | 0 (0.0%) | 2 (1.0%) | 2 (0.4%) | |
| Moderately differentiated | 36 (13.7%) | 47 (23.9%) | 83 (18.0%) | |
| Poorly differentiated | 190 (72.2%) | 126 (64.0%) | 316 (68.7%) | |
| Undifferentiated | 37 (14.1%) | 22 (11.2%) | 59 (12.8%) | |
| Number of Positive Nodes | 0.317 | |||
| Mean (SD) | 2.15 (3.85) | 2.06 (3.96) | 2.11 (3.90) | |
| Ratio of Positive Nodes/Total Number | 0.306 | |||
| Mean (SD) | 0.15 (0.21) | 0.18 (0.48) | 0.16 (0.35) | |
| Stage at Diagnosis | 0.907 | |||
| I | 48 (17.6%) | 36 (17.2%) | 84 (17.4%) | |
| II | 220 (80.6%) | 168 (80.4%) | 388 (80.5%) | |
| III | 5 (1.8%) | 5 (2.4%) | 10 (2.1%) | |
| Adjuvant Chemotherapy | 0.752 | |||
| Yes | 230 (85.2%) | 169 (86.2%) | 399 (85.6%) | |
| Adjuvant Radiotherapy | 0.122 | |||
| Yes | 189 (69.2%) | 130 (62.5%) | 319 (66.3%) |
*
P-values for categorical variables were calculated using a Pearson chi-square test. A Kruskal-Wallis test was used for continuous variables.