Table 5.
Model-based toxicity risk ↓ | Full cohort, N = 464a
|
Standard dose, N = 360
|
Primary dose reduction, N = 104
|
||||||
---|---|---|---|---|---|---|---|---|---|
N | % | p-Value | N | % | p-Value | N | % | p-Value | |
Low | 39/128 | 30 | <0.0001 | 29/96 | 30 | <0.0001 | 10/32 | 31 | 0.0012 |
Medium | 118/227 | 52 | 96/182 | 53 | 22/45 | 49 | |||
High | 90/109 | 83 | 69/82 | 84 | 21/27 | 78 |
Sample size reflects patients who had complete data for the 11 variables comprising the CARG toxicity score.