Table 2. TBSS findings.
Cluster size | PFWE | Co-ord | Peak region |
---|---|---|---|
Effects of translocation (family members without (n = 13) > with (n = 7) translocation) | |||
Non-carriers (n = 13) > carriers (n = 7) | |||
1) 921 | 0.042 # (0.039)* | -3 28 6 | L genu of corpus callosum |
2) 63 | 0.049 # (0.056)* | 29 26 15 | R inferior fronto-occipital fasciculus |
3) 55 | 0.049 # (0.046)* | 11 26 14 | R genu of corpus callosum |
4) 38 | 0.040 # (0.037)* | 20–25 0 | R acoustic radiation |
5) 23 | 0.049 # (0.035)* | 28–24–8 | R fornix |
Effects of psychosis (controls (n = 33) > psychosis patients (n = 34)) | |||
1) 31818 | 0.008 | -6–31 22 | R/L splenium body and genu of corpus callosum |
2) 437 | 0.047 | 29 16–6 | R external capsule, inferior fronto-occip fasciculus, uncinate fasciculus |
3) 294 | 0.047 | -1–5 13 | R/L fornix |
reverse contrasts of carriers > non-carriers and psychosis patients > controls: not significant.
#peak also significant for the controls > patient analysis, see text for further details.
*number in brackets represents p values for at the same co-ordinate for the analysis removing the younger individuals from the non-carrier group.