Table 3.

Lung cancer risk among bricklayers in studies using population controls, the SYNERGY study, 1985–2010

	Cases	Controls	OR1	(95% CI)	OR2	(95% CI)	OR3	(95% CI)
All men	11,762	14,519
Never bricklayers	11,222	14,170	1.00	(Reference)	1.00	(Reference)
Never bricklayers, blue collars	8,816	9,512					1.00	(Reference)
Ever bricklayers	540	349	1.55	(1.32–1.81)	1.35	(1.15–1.59)	1.43	(1.22–1.68)
Length of employment as bricklayers
<10 years	229	187	1.15	(0.92–1.43)	1.03	(0.82–1.29)	1.07	(0.86–1.34)
10–19 years	92	43	1.85	(1.23–2.78)	1.59	(1.06–2.39)	1.70	(1.13–2.55)
20–29 years	73	35	2.41	(1.51–3.87)	2.08	(1.30–3.34)	2.19	(1.37–3.52)
30–39 years	76	31	2.87	(1.77–4.66)	2.38	(1.47–3.85)	2.61	(1.61–4.24)
≥40 years	65	45	1.83	(1.17–2.86)	1.54	(0.98–2.41)	1.68	(1.07–2.63)
Unknown	5	8	–	–	–	–	–	–
Test for linear trend (p-value)			<0.001		<0.001		<0.001
Test for linear trend among bricklayers only (p-value)			0.001		0.003		–1
Length of employment as bricklayers, log(years)
Among all subjects	11,757	14,511	1.23	(1.15–1.30)	1.17	(1.10–1.24)	1.19	(1.12–1.27)
Among bricklayers only	535	341	1.38	(1.16–1.65)	1.33	(1.11–1.60)	–1
Lung cancer morphology
Squamous cell carcinoma	233		1.77	(1.46–2.14)	1.47	(1.21–1.79)	1.60	(1.32–1.95)
Small cell carcinoma	109		1.86	(1.46–2.37)	1.58	(1.24–2.03)	1.66	(1.30–2.12)
Adenocarcinoma	120		1.23	(0.98–1.55)	1.15	(0.91–1.46)	1.18	(0.93–1.48)
Test of homogeneity (p-value)			0.004		0.06		0.02

Lists A/B, occupations known (list A) or suspected (list B) to be associated with lung cancer; CI, confidence interval; OR1, odds ratio adjusted for study center, age, smoking, lists A/B; OR2, odds ratio adjusted for study center, age, smoking, lists A/B occupations, education; OR3, odds ratio adjusted for study center, age, smoking, lists A/B occupations, with blue collar workers as reference.

¹Same as OR1 analysis.