Table 4.

Lung cancer risk among bricklayers in studies using hospital/mixed controls, the SYNERGY study, 1985–2010

	Cases	Controls	OR1	(95% CI)	OR2	(95% CI)	OR3	(95% CI)
All men	3,846	4,012
Never bricklayers	3,691	3,892	1.00	(Reference)	1.00	(Reference)
Never bricklayers, blue collars	2,934	2,763					1.00	(Reference)
Ever bricklayers	155	120	1.24	(0.93–1.64)	1.18	(0.89–1.58)	1.19	(0.90–1.59)
Length of employment as bricklayers
<10 years	49	38	1.56	(0.95–2.57)	1.52	(0.92–2.52)	1.49	(0.90–2.45)
10–19 years	19	20	0.82	(0.40–1.69)	0.79	(0.38–1.62)	0.80	(0.39–1.64)
20–29 years	15	20	0.74	(0.35–1.58)	0.66	(0.31–1.42)	0.72	(0.34–1.54)
30–39 years	23	14	1.45	(0.67–3.16)	1.45	(0.66–3.19)	1.41	(0.65–3.06)
≥40 years	24	10	1.67	(0.72–3.91)	1.61	(0.68–3.80)	1.63	(0.69–3.81)
Unknown	25	18	–	–	–	–	–	–
Test for linear trend (p-value)			0.24		0.36		0.32
Test for linear trend among bricklayers only (p-value)			0.93		0.86		–1
Length of employment as bricklayers, log (years)
Among all subjects	3,821	3,994	1.07	(0.96–1.19)	1.05	(0.94–1.17)	1.06	(0.95–1.18)
Among bricklayers only	130	102	0.87	(0.60–1.25)	0.90	(0.61–1.30)	–1
Lung cancer morphology
Squamous cell carcinoma	76		1.41	(1.01–1.97)	1.30	(0.93–1.83)	1.33	(0.95–1.87)
Small cell carcinoma	31		1.59	(1.02–2.48)	1.48	(0.94–2.32)	1.54	(0.99–2.41)
Adenocarcinoma	30		0.97	(0.63–1.51)	0.99	(0.63–1.54)	0.96	(0.62–1.50)
Test of homogeneity (p-value)			0.16		0.31		0.21

Lists A/B, occupations known (list A) or suspected (list B) to be associated with lung cancer; CI, confidence interval; OR1, odds ratio adjusted for study center, age, smoking, lists A/B; OR2, odds ratio adjusted for study center, age, smoking, lists A/B occupations, education; OR3, odds ratio adjusted for study center, age, smoking, lists A/B occupations, with blue collar workers as reference.

¹Same as OR1 analysis.