Table 1.

Patient characteristics

Clinical Parameter	Cohort 1 (No.)	Cohort 2 (No.)
Specimens	149	101
Mean age	54.7	58.6
Age
≤54	67	37
>54	82	64
Gender
Male	112	80
Female	37	21
Tumor size (cm)
≤3	39	29
3–5	79	47
>5	31	25
Histologic grade
G1	29	13
G2	99	77
G3	21	11
Invasive depth
T1	1	2
T2	21	11
T3	123	86
T4	4	2
Lymph node metastasis
N0	87	44
NI + N2+ N3	62	57
TNM classification
I
IA	1	1
IB	3	3
II
IIA	31	12
IIB	51	31
III
IIIA	50	29
IIIB	3	16
IIIC	1	0
IV
IV	9	0