Table 4. Association between air pollutants and components of metabolic syndrome.
Fasting time (hours) | 10-year mean PM10 OR (95%CI) | P-value | 10-year mean NO2 OR (95%CI) | P-value | |
---|---|---|---|---|---|
Impaired fasting Glycaemia (IFG;WHO) | 4 | 1.82 (1.60, 2.08) | <0.001 | 1.15 (0.98, 1.34) | 0.080 |
8 | 2.27 (1.43, 3.62) | 0.001 | 1.33 (0.98, 1.79) | 0.063 | |
Impaired fasting Glycaemia (IFG; IDF/ATP-III) | 4 | 1.45 (1.19, 1.78) | <0.001 | 1.06 (0.93, 1.21) | 0.388 |
8 | 1.84 (1.30, 2.60) | 0.001 | 1.36 (1.08, 1.72) | 0.008 | |
Low high-density lipoproteins (WHO) | 4 | 0.95 (0.76, 1.19) | 0.657 | 0.88 (0.76, 1.01) | 0.071 |
8 | 0.89 (0.47, 1.70) | 0.735 | 0.76 (0.49, 1.19) | 0.229 | |
Low high-density lipoproteins (IDF/ATP-III) | 4 | 0.99 (0.87, 1.12) | 0.847 | 0.95 (0.87, 1.05) | 0.303 |
8 | 0.99 (0.63, 1.56) | 0.982 | 0.86 (0.66, 1.13) | 0.287 | |
High triglycerides | 4 | 0.90 (0.77, 1.05) | 0.169 | 0.94 (0.85, 1.03) | 0.194 |
8 | 1.14 (0.78, 1.67) | 0.494 | 0.94 (0.73, 1.21) | 0.630 | |
Hypertension (WHO) | 4 | 1.12 (0.97, 1.29) | 0.130 | 1.11 (1.01, 1.20) | 0.022 |
Hypertension (IDF/ATP-III) | 4 | 1.11 (0.95, 1.30) | 0.172 | 1.12 (1.03, 1.23) | 0.011 |
Central obesity (BMI>30kg/m2) | 4 | 1.00 (0.83, 1.21) | 0.971 | 1.01 (0.89, 1.14) | 0.898 |
Central obesity a | 4 | 1.19 (0.90, 1.58) | 0.218 | 1.06 (0.90, 1.26) | 0.465 |
Fully adjusted models include age, sex, educational attainment, neighbourhood socio-economic index, occupational exposure to vapours, gases, dusts and fumes, smoking status, smoked pack-years, exposure to passive smoke, consumption of fruits and raw vegetables, physical activity and body mass index (BMI). Model for obesity excludes BMI. PM10: particulate matter <10μm in diameter from all sources. NO2: nitrogen dioxide. Traffic PM10 refers to dispersion models including only traffic-related emissions. OR: odds ratio. CI: confidence interval. OR values represent fold increase in odds of outcomes per 10μg/m3 of PM10, NO2, and 1μg/m3 of traffic PM10 exposure. IFG defined as fasting blood glucose≥6.1mmol/L and/or diagnosis of type2diabetes. High triglycerides defined as fasting triglycerides≥1.7mmol/L or treatment for this condition. Low HDL defined by IDF and ATP-III as < 1.03 mmol/L (males), < 1.29 mmol/L (females), or treatment for this condition, and by WHO as ≤ 0.9 mmol/L (males), ≤ 1.0 mmol/L (females). Hypertension defined by IDF and ATP-III as blood pressure >130/85 mm Hg and by WHO as ≥140/90, or treatment of previously diagnosed hypertension. Participants’ study area was treated as a random effect in all models. N (4 hours fasting time) = 3684. N (8 hours fasting time) = 367.
aCentral obesity defined using the predicted waist circumference and European cut-offs (≥94cm for males and ≥80cm for females)