Fig 7. Liver eEF1A-1 Protein is Increased in Obese Mice with Severe Hepatic Steatosis and ER stress.

(A) 6 week old male wild type (C57BL/6J) or leptin-deficient (ob/ob) mice were maintained on AIN-76A diet for 4 weeks. eEF1A-1, GRP78, and actin proteins were detected by immunoblotting whole tissue homogenates from liver, and quantified by densitometry. Representative blots are shown. Data are means ± SEM for n = 8, * p < 0.05. (B, C) Representative images of Oil Red O and H&E stained frozen liver tissue sections from C57BL/6J (top panels) and ob/ob (bottom panels) mice. Scale bar represents 100 μm.