Table 2. Factors associated with IL-6 and CRP in the 83 HCV-infected women.
All HCV-infected women | ||||
---|---|---|---|---|
| ||||
IL-6 | CRP | |||
| ||||
Unadjusted | Adjusted* | Unadjusted | Adjusted** | |
% difference (95%CI), p-value | % difference (95%CI), p-value | |||
Demographic Factors | ||||
Age (per decade) | 16% (-34%, 101%) p=0.61 |
23% (-18%, 84%) p=0.31 |
37% (-27%, 126%) p=0.22 |
3% (-38%, 73%) p=0.90 |
Black (vs. Caucasian) | 99% (-49%, 674%) p=0.319 |
54% (-37%, 279%) p=0.343 |
39% (-52%, 301%) p=0.544 |
40% (-46%, 264%) p=0.495 |
Hispanic (vs. Caucasian) | 36% (-76%, 669%) p=0.731 |
71% (-48%, 466%) p=0.374 |
11% (-72%, 351%) p=0.879 |
18% (-67%, 329%) p=0.797 |
Metabolic Factors | ||||
Waist Circumference (per 10cm) | 2% (-1%, 4%) p=0.14 |
0% (-2%, 3%) p=0.74 |
4% (2%, 6%) p<0.0001 |
4% (2%, 6%) p<0.0001 |
HCV-Related Factors | ||||
Liver Stiffness (per doubling) | 31% (-1%, 74%) p=0.06 |
34% (8%, 66%) p=0.009 |
33% (4%, 70%) p=0.02 |
21% (-6%, 57%) p=0.141 |
HCV RNA (per doubling) |
-20% (-27%, -12%) p<0.0001 |
-16% (-30%, 1%) p=0.06 |
-7% (-26%, 3%) p=0.17 |
-9% (-18%, 0%) p=0.05 |
Outcomes are log-transformed; results are back-transformed to produce estimated relative differences in inflammatory marker attributable to each factor. Estimates are from multivariable Poisson regression models.