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. 2015 Apr 2;36(7):2691–2702. doi: 10.1002/hbm.22800

Table 1.

Corpus Callosum Measures

Mean (SD) values Age at peak value Linear slopea
Sexes combined (n = 305) Men (n = 160) Women (n = 145) Sexes Combined (n = 305) Men (n = 160) Women (n = 145) Before age peak After age peak
Area 621.5 (98.9) 637.4 (99.7) 603.9 (95.4) 40.80 38.63 42.31 0.450** −0.091
Perimeter 203.8 (16.9) 206.3 (17.9) 201.0 (15.3) 51.18 50.31 50.70 0.408** 0.089
Circularity 0.188 (0.023) 0.189 (0.024) 0.187 (0.021) 19.50 8.13 29.82 N/Ab (m) −0.001 (f) −0.318** (m) −0.276 (f)
Length 73.7 (5.2) 74.3 (5.4) 73.1 (4.9) 45.02 45.02 44.25 0.410** 0.029
Subregions
Witelson 1 21.6 (8.8) 22.9 (9.9) 20.3 (7.2) 49.43 48.61 47.59 0.337** 0.193
Witelson 2 137.9 (27.9) 141.4 (30.0) 134.3 (24.8) 35.75 32.19 40.07 0.193 (m) 0.376**(f) −0.292* (m) −0.172 (f)
Witelson 3 88.5 (16.1) 90.7 (15.8) 86.0 (16.2) 41.88 40.78 43.26 0.324** −0.017
Witelson 4 72.7 (12.8) 74.7 (12.7) 70.5 (12.7) 40.78 38.63 41.88 0.465** −0.120
Witelson 5 62.2 (11.4) 63.8 (11.1) 60.5 (11.6) 40.16 38.63 41.62 0.423** −0.141
Witelson 6 52.7 (12.5) 54.5 (12.0) 50.7 (12.7) 38.63 35.33 40.07 0.257** −0.110
Witelson 7 185.8 (30.3) 189.5 (31.6) 181.7 (28.4) 45.23 45.02 45.23 0.359** −0.074
Hampel 1 194.2 (29.9) 198.2 (32.0) 189.7 (26.6) 38.26 36.87 40.07 0.392** −0.337**
Hampel 2 86.9 (19.3) 89.9 (18.9) 83.5 (19.2) 38.26 35.33 41.88 0.257** −0.196
Hampel 3 71.2 (16.9) 73.9 (15.6) 68.2 (17.7) 43.26 40.78 45.23 0.288** −0.045
Hampel 4 75.1 (20.3) 78.9 (18.9) 70.9 (21.0) 45.23 41.35 45.23 0.179** −0.127
Hampel 5 194.1 (30.4) 196.5 (31.7) 191.5 (28.7) 42.97 42.56 42.91 0.428** 0.007
Intracranial Vol (mm3) 1,528,168 (182,975) 1,619,129 (160,564) 1,427,796 (151,247)

Note: Univariate statistics are reported for descriptive purposes only.

a

Slope reported separately for females (f) and males (m) where a significant age by sex interaction was found.

b

Slope not reported due to an insufficient number of males younger than the peak age.

*Correlation is significant at the 0.05 level (two‐tailed); **Correlation is significant at the 0.01 level (two‐tailed).