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Receptor binding and metabolic and mitogenic properties of insulin aspart and insulin degludec
| Human insulin | Insulin degludec | Insulin aspart | |
|---|---|---|---|
| Insulin receptor affinity | 100% | 13–15% | 92% |
| IGF receptor affinity | 100% | 2% | 81% |
| Metabolic potency | 100% | 8–20% | 101% |
| Mitogenic potency | 100% | 4–14% | 58% |
| Mitogenic/metabolic potency ratio | 1 | <1 | <1 |
