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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Mov Disord. 2015 Mar 24;30(7):936–944. doi: 10.1002/mds.26172

Figure 3.

Figure 3

PD CSF levels stratified by APOE and SNP. There is a significant difference in CSF Aβ42 levels between APOE ε4+ rs466448 G+ and APOE ε4− rs466448 G− (p=0.030) as well as between APOE ε4− rs466448 G+ and APOE ε4− rs466448 G− (p=0.035) (Panel A). There is a significant difference in CSF Aβ42 levels between APOE ε4+ rs2068143 A− and APOE ε4− rs2068143 A+ (p=0.027) as well as between APOE ε4− rs2068143 A− and APOE ε4− rs2068143 A+ (p=0.021) (Panel B). Bars represent interquartile range for CSF Aβ42 levels and width of bars a adjusted for number of subjects. P-values are adjusted for covariates gender and age. P-values in parentheses are not adjusted for covariates and bar graphs are not adjusted for covariates. The horizontal line within the quartiles represents the median. The vertical lines represent minimum and maximum CSF Aβ42 levels. Circles represent outliers. All p-values are Bonferroni corrected for multiple comparisons.