Table 5.

Relative risk (RR) of total and lethal prostate cancer in relation to onset of hayfever by age at prostate cancer diagnosis and cigarette smoking in the past 10 years, Health Professionals Follow-up Study 1986-2012

	Hayfever onset relative to baseline						No hayfever
	Recent past (<30 years ago)			Distant past (≥30 years ago)
	Cases	Person- years	Age-adjusted RR (95% CI)	Cases	Person- years	Age-adjusted RR (95% CI)	Cases	Person- years
Total Prostate Cancer
Age at prostate cancer diagnosis
Younger (<60 years)	99	50,868	1.12 (0.90-1.39)	132	55,574	1.38a (1.13-1.67)	484	280,065
Older (≥60 years)	448	52,506	1.00 (0.90-1.10)	958	97,974	1.07a (1.00-1.15)	4,173	458,371
Cigarette smoking in the past 10 years
No	501	90,874	1.02 (0.92-1.11)	960	134,403	1.06b (0.99-1.14)	4,106	624,699
Yes	46	12,500	0.93 (0.69-1.27)	130	19,145	1.45b (1.19-1.75)	551	113,738
Lethal Prostate Cancer
Age at prostate cancer diagnosis
Younger (<60 years)	7	50,868	0.77 (0.35-1.70)	9	55,574	0.73 (0.36-1.49)	56	280,065
Older (≥60 years)	45	52,506	0.98 (0.72-1.33)	129	97,974	1.14 (0.94-1.38)	552	458,371
Cigarette smoking in the past 10 years
No	44	90,874	0.94 (0.69-1.28)	117	134,403	1.07 (0.88-1.31)	509	624,699
Yes	8	12,500	1.02 (0.49-2.10)	21	19,145	1.41 (0.88-2.27)	99	113,738

^ap-interaction=0.02

^bp-interaction=0.003