Table 4.
N2 | pgrn-1(-); TDP-43 | pgrn-1(-); gran1 | pgrn-1(-); gran1; TDP-43 | pgrn-1(-); gran2 | pgrn-1 (-); gran2; TDP-43 | pgrn-1 (-); gran3 | |
---|---|---|---|---|---|---|---|
N2 | — | — | — | — | — | — | — |
pgrn-1(tm985) | ns | — | — | — | — | — | — |
N2;TDP-43 | *** | — | — | — | — | — | — |
pgrn-1(-);TDP-43 | *** | — | — | — | — | — | — |
pgrn-1(-);gran1 | ns | *** | — | — | — | — | — |
pgrn-1(-);gran1;TDP-43 | *** | ns | ** | — | — | — | — |
pgrn-1(-);gran2 | ns | *** | ns | *** | — | — | — |
pgrn-1(-);gran2;TDP-43 | *** | *** | *** | *** | *** | — | — |
pgrn-1(-);gran3 | ns | *** | ns | *** | ns | *** | — |
pgrn-1(-);gran3;TDP-43 | *** | *** | *** | *** | *** | ns | *** |
Thrashing scores were compared by one-way ANOVA with a Bonferroni correction (ns, not significant;
**p < 0.05,
***p < 0.0001).