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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Pharmacogenomics J. 2014 Dec 23;15(4):354–362. doi: 10.1038/tpj.2014.73

Table 3.

ERCC1, TS, EGFR, VEGFR2 Gene Expression Levels by KRAS and BRAF Mutation Status

KRAS Mutation Status BRAF Mutation Status


Mutant Wildtype Mutant Wildtype




Gene N Median (range) N Median (range) N Median (range) N Median (range)
ERCC1 176 0.87 (0.23–2.96) 211 0.98 (0.17–6.66) 35 0.94 (0.28–2.47) 356 0.91 (0.20–6.66)
  P value* 0.01 0.35
TS 174 2.08 (0.52–21.43) 209 2.38 (0.65–18.99) 34 3.38 (1.01–13.81) 352 2.17 (0.52–21.43)
  P value* 0.03 <0.001
EGFR 175 1.61 (0.33–7.17) 208 2.06 (0.63–71.28) 33 2.20(1.12–3.50) 349 1.75 (0.33–71.28)
  P value* <0.001 0.002
VEGFR2 117 1.19 (0.23–7.66) 158 1.35 (0.18–13.00) 26 1.48 (0.29–3.41) 252 1.25 (0.18–13.0)
  P value* 0.003 0.64
*

Based on Kruskal-Wallis test.