Table 1.
Characteristics of the cognitively healthy elderly in the Swedish BioFinder study compared with the MDCS re-examination cohort
| Characteristics | n | Cognitively healthy (n = 208) | MDCS (n = 3,526) | p value |
|---|---|---|---|---|
| Age, years | 3,734 | 71 ± 4.8 | 73 ± 5.6 | <0.001 |
| Male sex | 3,734 | 85 (41) | 1,437 (41) | 0.98 |
| Higher education | 3,619 | 104 (51) | 1,037 (30) | <0.001 |
| Ever smoking | 3,614 | 127 (62) | 1,842 (54) | 0.033 |
| Waist/hip ratio | 3,696 | 0.89 ± 0.1 | 0.90 ± 0.1 | 0.361 |
| Sedentary lifestyle | 3,679 | 5 (2.4) | 298 (8.6) | 0.002 |
| Systolic blood pressure, mm Hg | 3,694 | 137 ± 17 | 144 ± 19 | <0.001 |
| Diastolic blood pressure, mm Hg | 3,692 | 82 ± 10 | 83 ± 10 | 0.31 |
| Total cholesterol, mmol/l | 3,692 | 5.3 ± 1.1 | 5.2 ± 1.1 | 0.07 |
| Fasting plasma glucose, mmol/l | 3,694 | 5.9 ± 1.0 | 6.2 ± 1.5 | 0.006 |
| Cardiovascular disease | 3,127 | 12 (6.7) | 478 (16) | 0.001 |
| PWV, m/s | 3,056 | 10.0 ± 2.0 | 11.±2.5 | 0.001 |
| MMSE score | 3,329 | 29 ± 0.8 | 28 ± 1.9 | <0.001 |
| AQT, s | 3,310 | 65 ± 11 | 75 ± 21 | <0.001 |
| Blood pressure-lowering medication | 3,734 | 86 (41) | 1,796 (51) | 0.007 |
| Lipid-lowering medication | 3,734 | 57 (27) | 1,072 (30) | 0.36 |
| Antidiabetic medication | 3,734 | 13 (6.3) | 300 (8.5) | 0.25 |
| Antiplatelet medication (ASA) | 3,734 | 28 (14) | 861 (24) | <0.001 |
| Anticoagulant medication (warfarin) | 3,734 | 9 (4.3) | 165 (4.7) | 0.82 |
Values are presented as mean ± SD or n (%). Group differences were analysed using the independent samples t test (numeric variables) or χ2 test (categorical variables). ASA = Acetylsalicylic acid; AQT = A Quick Test of Cognitive Speed.
1
p value on log data.