Table 3.

Cellular specificity of CCN protein expression in selected regions of the CNS according to the Human Protein Atlas.

	Cerebral cortex	Hippocampus	Lateral ventricle	Cerebellum
CCN1	endothelial cells—medium glial cells—low neuronal cells—medium neuropil—medium	glial cells—not detected neuronal cells—medium	glial cells—low neuronal cells—medium	cells in granular layer—medium cells in molecular layer—low Purkinje cells—high
CCN2	endothelial cells—medium glial cells—medium neuronal cells—medium neuropil—medium	glial cells—low neuronal cells—medium	glial cells—low neuronal cells—medium	cells in granular layer—medium cells in molecular layer—medium Purkinje cells—medium
CCN3	endothelial cells—not detected glial cells—not detected neuronal cells—not detected neuropil—not detected	glial cells—not detected neuronal cells—not detected	glial cells—not detected neuronal cells—not detected	cells in granular layer—not detected cells in molecular layer—not detected Purkinje cells—not detected
CCN4	endothelial cells—high glial cells—medium neuronal cells—medium neuropil—medium	glial cells—medium neuronal cells—medium	glial cells—medium neuronal cells—medium	cells in granular layer—medium cells in molecular layer—medium Purkinje cells—high
CCN5	endothelial cells—not detected glial cells—not detected neuronal cells—medium neuropil—not detected	glial cells—not detected neuronal cells—medium	glial cells—not detected neuronal cells—not detected	cells in granular layer—not detected cells in molecular layer—not detected Purkinje cells—not detected
CCN6	not analyzed	not analyzed	not analyzed	not analyzed