Table 1.

Significant associations between patient characteristics and radiographic progression in 7 studies of 5 cohorts.

		Ramiro 2015 [2]	Ramiro 2014 [13]	Kang 2014 [6]	Braun 2013 [3]	Poddubnyy 2013 [10]	Chung 2012 [11]*	Tubergen 2012 [12]
Methods	Cohort	OASIS	OASIS	67 women	GO-RAISE	GESPIC	DESIR	OASIS
	Outcome	Change in mSASSS	Change in mSASSS	New syndesmophytes	Change in mSASSS	mSASSS and new syndesmophytes	mSASSS	New syndesmophytes
	Statistics	Multivariate	Univariate	Univariate	Univariate	Multivariate	Multivariate	Multivariate
Results	Existing syndesmophytes	yes	yes	yes	yes	-	-	yes
	CRP	-	yes	yes	yes	-	yes	no
	Male gender	yes	-	-	-	-	yes	-
	Smoking	-	-	-	-	yes	yes	-
	Older age	-	-	yes	-	-	-	no
	HLA-B27	yes	no	-	-	-	no	no
	Disease duration	no	-	yes	-	-	-	no
	Symptom duration	no	-	-	-	-	-	no
	Family history	-	-	-	-	-	yes	-
	Sacroiliitis severity	-	-	yes	-	-	-	-
	Age at onset of IBP	-	-	-	-	-	yes	-
	BASDAI	-	yes	-	-	-	-	no
	ASDAS	-	yes	-	-	-	-	no
	Hip involvement	-	-	-	-	-	-	no
	Extra-articular manifestation	-	no	-	-	-	-	-
	ESR	-	no	-	-	-	-	no

^*Indicates a cross-sectional study. Other studies are longitudinal.

(-) not studied or reported.

OASIS: Outcome in Ankylosing Spondylitis International Study; GO-RAISE: phase III clinical trial of Golimumab; GESPIC: German Spondyloarthritis Inception Cohort; DESIR: Devenir des Spondylarthropathies Indifférenciées Récentes; ; CRP: C-reactive protein; IBP: inflammatory back pain; BASDAI: Bath ankylosing spondylitis disease activity index; ASDAS: AS disease activity score; Extra-articular manifestations include psoriasis, inflammatory bowel disease and uveitis; ESR: erythrocyte sedimentation rate.