FIG 3.

Reactivity of JWW-1 and JWW-2 human chimeric monoclonal antibodies with L2 of diverse HPV, as determined by Western blotting. Pseudovirion preparations of 34 clinically relevant alpha- and beta-HPV types were separated by SDS-PAGE and transferred to a membrane. The reactivity of JWW-1 or JWW-2 against L2 of each type was determined by probing with peroxidase-linked anti-human IgG for JWW-1 and JWW-2 or peroxidase-linked anti-rabbit IgG for the L2α 11-88x8 antiserum. After washing, these Western blots were developed by chemiluminescence.