TABLE 3.
Characteristics of the cohort of 160 women with high-grade CIN enrolled in a natural history study (33) and treated at Johns Hopkins University, Baltimore, MD, USA
| Diagnosisa | No. (%) of patients |
|---|---|
| HGSIL | 132 (82.5) |
| Benign/CCSM | 11 (6.9) |
| ASCUS | 2 (1.3) |
| ASC-H | 2 (1.3) |
| AIM | 1 (0.6) |
| LSIL-H | 1 (0.6) |
| LSIL | 11 (6.9) |
| HPV16 status (HGSILs only) | |
| HPV16+ | 87 (54.4) |
| HPV16− | 42 (26.3) |
| Not done | 3 (1.9) |
| HPV16 status (all patients) | |
| HPV16+ | 99 (61.9) |
| HPV16− | 53 (33.1) |
| Not done | 7 (4.4) |
| Indeterminate | 1 (0.6) |
| Race/ethnicity | |
| White | 109 (68.1) |
| Black | 37 (23.1) |
| Asian | 5 (3.1) |
| Hispanic | 9 (5.6) |
| Age group (yr) | |
| 18–20 | 16 (10.0) |
| 21–30 | 86 (53.8) |
| 31–40 | 39 (24.4) |
| 41–50 | 13 (8.1) |
| ≥50 | 6 (3.8) |
a
Serum samples were collected at the screening visit and at subsequent treatment and follow-up visits when available. HGSIL, high-grade squamous intraepithelial lesion; CCSM, cervical cancer-specific mortality; ASC-H, high-grade atypical squamous cells; AIM, atypical immature squamous metaplasia; LSIL-H; high-grade squamous intraepithelial lesion; LSIL, low-grade squamous intraepithelial lesion.