TABLE 7.
Performance of the HISCL anti-TP assay compared with other treponemal assays based on CLIA
| Assay | Antigen(s) | Antibody target(s) | Sample vol (μl) | Assay time (min) | Throughput time (h) |
|---|---|---|---|---|---|
| HISCL anti-TP | TpN15, TpN17, TpN47 | IgG, IgM | 20 | 17 | 200 |
| Elecsys syphilis (17) | TpN15, TpN17, TpN47 | IgG, IgM | 10 | 18 | 170 |
| Architect syphilis TP (4, 27, 28) | TpN15, TpN17, TpN47 | IgG, IgM | 30 | 29 | 200 |
| Liaison Treponema pallidum specific (24, 29) | TpN17 | IgG, IgM | 80 | 40 | 180 |
| Chemclin CLIA (30) | TpN15, TpN17, TpN47 | naa | na | ≥60 | na |
| Immulite syphilis screen (9) | Tp17 | na | 100 | 35 | na |
a
na, not applicable.