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. 2015 Mar 30;5(6):1043–1056. doi: 10.1534/g3.115.017913

Figure 2.

Figure 2

Quantitative performance of the quantitative chromosome transmission fidelity (qCTF) assay. (A) A table comparing the qCTF assay with the a-like faker (ALF) assay and CTF assay in detecting the rate of elevation of chromosome instability (CIN) caused by loss-of-function/deletion of MAD1. For qCTF assay, the data were shown as Mean ± SEM, n = 8. (B) Box-and-whisker plots showing the effect of different chemicals on CIN. P-values were calculated from the Mann–Whitney U test with n = 8. *P < 0.05; ***P < 0.001. DMSO, dimethyl sulfoxide; MMS, methyl methanesulfonate; CAT, carboxyatractyloside.