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. 2015 Jun 25;6(6):880–888. doi: 10.4239/wjd.v6.i6.880

Table 1.

List of included studies, all describing pregnancy and neonatal outcomes in Indigenous Australians with diabetes in pregnancy

Ref. Year Title Study region Years studied Total study size Total women with DIP Number of Indigenous women with DIP Outcome measured Findings
Stanley et al[25] 1985 Congenital malformations in infants of mothers with diabetes and epilepsy in Western Australia, 1980-1982 WA 1980-1982 62265 225 52 Congenital anomalies Relative risk of malformations in Aboriginal DIP - 5.6 compared to 1.9 in non-Aboriginal DIP. Attributable risk however, is low
Bower et al[24] 1992 Birth defects in the infants of Aboriginal and non-Aboriginal mothers with diabetes in Western Australia WA 1980-1984 111019 427 98 Congenital anomalies Prevalence ratio for birth defects in Aboriginal children is 4.85 for insulin dependent DM and 3.64 for non-insulin dependent DM, compared to 2.08 and 3.64 respectively for non-Aboriginal children
Blair[23] 1996 Why do Aboriginal newborns weigh less? Determinants of birthweight for gestation WA 1980's 1301 672 159 Birth weight Aboriginal newborns weigh 180 g less than non-Aboriginal (DIP and non-DIP)
Sharpe et al[22] 2005 Maternal Diabetes and Congenital Anomalies in South Australia 1986-2000: A Population-Based Cohort Study SA 1986-2000 282260 7681 432 Congenital anomalies Congenital anomalies significantly higher in mothers with DIP, relative risk 2.01. No difference with ethnicity
Davis et al[28] 2009 Maternal and neonatal outcomes following diabetes in pregnancy in Far North Queensland, Australia North Queensland 2004 506831 136 59 C-section, hypoglycaemia, resp distress, abnormal birth weight, term delivery Compared with non-Indigenous women, Indigenous women had smaller babies, less term deliveries, more severe neonatal hypoglycaemia. Worse outcomes than national and state data
Falhammar et al[19] 2010 Maternal and neonatal outcomes in the Torres Strait Islands with a sixfold increase in type 2 diabetes in pregnancy over six years North Queensland 1999, 2005/2006 454 37 32 C-section, large baby, neonatal trauma, hypoglycaemia DIP infants heavier (700 g), taller (1.9 cm), more neonatal trauma and hypoglycaemia
Porter et al[26] 2011 What is the impact of diabetes for Australian Aboriginal women when pregnant? WA 2000-2007 81617 5987 531 Birth weight, C-section, stillbirth Indigenous infants’ high birth weight, stillbirth rate = 22/1000 for GDM and 53/1000 for pre-existing DM, compared with 3/100 and 11/1000 for Caucasians
Davis et al[29] 2013 A threefold increase in gestational diabetes over two years: Review of screening practices and pregnancy outcomes in Indigenous women of Cape York, Australia North Queensland 2006, 2008 261 31 31 C-section, birth weight, hypoglycaemia Higher rates of C-section (66 vs 25%), higher birth weight and increased rate of hypoglycaemia (> 40%) in DIP vs non-DIP Indigenous mothers and babies
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136 local mothers were compared to diabetic mothers in a national benchmark study (n = 496) and to all pregnant data in Queensland 2004 (n = 50051). DIP: Diabetes in pregnancy; C-section: Caesarean section.