. Author manuscript; available in PMC: 2015 Jun 24.

Published in final edited form as: Diabetes Metab Res Rev. 2009 Nov;25(8):725–732. doi: 10.1002/dmrr.1010

Table 3.

Family History of MI and Covariates (in the Same Best Fitting Model) Associated with Incident CHD in the WHI-OS Diabetic Cohort

	All participants				White participants

	HR	L 95	U 95	P	HR	L 95	U 95	P
FHx MI in ≥2 relatives^a	1.79	1.36	2.35	<0.0001	1.60	1.16	2.20	0.004
1 relative^a	1.38	1.08	1.78	0.011	1.42	1.07	1.90	0.016
Age (year)	1.03	1.01	1.05	0.0005	1.03	1.01	1.05	0.005
SBP (mmHg)	1.01	1.003	1.02	0.001	1.01	1.002	1.02	0.018
DBP (mmHg)	0.98	0.97	0.999	0.005	0.98	0.97	0.998	0.026
Diab Meds (years)	1.03	1.02	1.05	<0.0001	1.04	1.02	1.06	<0.0001
White	1.49	1.16	1.93	0.002
Physical activity (2)	0.70	0.52	0.93	0.02	0.69	0.50	0.97	0.03
Physical activity (1)	0.81	0.62	1.06	0.13	0.79	0.58	1.08	0.14
Income <$50 000	1.42	1.07	1.89	0.01	1.46	1.07	2.00	0.02

Number of family relatives with MI compared with no family history of MI.

CHD, coronary heart disease; FHx, family history (reference group: no positive family history); MI, myocardial infarction; HR, hazard ratio; CI, confidence interval; SBP, systolic blood pressure; DBP, diastolic blood pressure; Diab Meds, years of diabetic medication use.

White: compared with all other racial groups; Physical activity: 0 = no walk outside for ≥20 min without stopping (reference group); 1 = <2 episodes/week; 2 = ≥2 episodes/week.