Table 3.

Serum NSE, S100b, MBP concentrations by good vs. poor outcome and mortality at 6 months.

Mean±SD [25th,75th %]	Median	All (n=43)	Good outcome (n=17)	Poor outcome (n=26)	p-value Good vs. Poor	Survived (n=26)	Died (n=17)	p-value Mortality
NSE (ng/ml)
Initial	15.40	26.9±33.4	16.1±20.6	33.9±38.4	0.047	14.5±16.9	45.7±43.1	0.003
		[5.8,34.0]	[3.0,25.2]	[10.8,46.3]		[3.5,17.7]	[14.3, 71.5]
Mean	29.92	38.2±38.2	14.6±18.9	53.6±39.9	<0.001	23.4±23.8	60.8±45.2	0.001
		[8.8,59.0]	[2.5,17.6]	[32.4,66.2]		[3.7,49.8]	[35.1, 75.1]
Median	28.00	34.4±37.3	13.7±19.4	47.8±40.3	<0.001	20.4±23.8	55.6±44.4	0.001
		[6.1,52.0]	[2.1,14.3]	2[29.3,55.2]		[3.1, 35.3]	[30.7, 60.4]
Peak	49.74	67.4±60.1	32.6±37.8	90.1±61.5	<0.001	49.4±45.6	94.8±70.0	0.015
		[16.7,101.0]	[5.8,38.6]	[48.2,117.5]		[9.5, 91.7]	[51.5, 52.1]
24 h	16.70	27.9±32.2	15.1±14.7	36.3±37.6	0.019	15.6±13.9	46.8±42.3	0.003
		[5.8,38.0]	[3.8,24.2]	[9.7,50.6]		[3.9, 22.3]	[15.1, 59.2]
48 h	34.18	44.4±52.7	20.4±24.6	60.8±60.5	0.011	25.2±28.6	75.8±67.4	0.007
		[4.0,60.0]	[2.9,38.4]	[22.9,74.8]		[3.2, 39.0]	[31.9, 115.7]
72 h	30.59	46.5±53.6	17.2±38.8	67.0±53.6	0.001	29.8±42.8	81.5±58.7	0.004
		[5.4,55.0]	[0.0,11.6]	[28.4,120.0]		[0.0, 49.6]	[42.8, 142.0]
S100b (ng/ml)
Initial	0.031	0.150±0.250	0.041±0.075	0.221±0.297	0.001	0.035±0.061	0.325±0.324	<0.001
		[0.009,0.190]	[0.005, 0.380]	[0.020, 0.290]		[0.007, 0.030]	[0.060, 0.660]
Mean	0.020	0.109±0.159	0.027±0.059	0.163±0.180	<0.001	0.024±0.047	0.239±0.181	<0.001
		[0.010,0.170]	[0.001, 0.019]	[0.010, 0.310]		[0.003, 0.020]	[0.070, 0.370]
Median	0.018	0.094±0.140	0.024±0.064	0.140±0.157	<0.001	0.021±0.052	0.260±0.158	<0.001
		[0.007,0.130]	[0.000, 0.010]	[0.010, 0.270]		[0.001, 0.010]	[0.060, 0.300]
Peak	0.048	0.196±0.277	0.064±0.099	0.283±0.321	0.001	0.055±0.081	0.412±0.331	<0.001
		[0.020,0.250]	[0.006, 0.060]	[0.030, 0.590]		[0.008, 0.050]	[0.110, 0.750]
24 h	0.021	0.107±0.181	0.023±0.038	0.162±0.215	<0.001	0.021±0.031	0.239±0.232	<0.001
		[0.008, 0.120]	[0.000, 0.020]	[0.010, 0.270]		[0.001, 0.210]	[0.040, 0.310]
48 h	0.019	0.113±0.191	0.034±0.075	0.167±0.227	0.001	0.029±0.061	0.251±0.248	<0.001
		[0.006, 0.200]	[0.001, 0.018]	[0.010, 0.210]		[0.002, 0.210]	[0.030, 0.430]
72 h	0.014	0.070±0.125	0.028±0.074	0.099±0.146	0.002	0.024±0.058	0.167±0.171	<0.001
		[0.003, 0.060]	[0.000, 0.010]	[0.010, 0.150]		[0.000, 0.020]	[0.010, 0.250]
MBP(ng/ml)
Initial	0.20	0.75±1.48	0.74±1.54	0.76±1.47	0.153	0.81±1.82	0.65±0.75	0.094
		[0.09,.44.00]	[0.07, 0.40]	[0.15, 0.72]		[0.08, 0.28]	[0.15, 1.11]
Mean	0.36	1.11±1.78	0.61±1.18	1.44±2.03	0.010	0.83±1.57	1.54±2.03	0.021
		[0.15,1.37]	[0.09,.40.00]	[0.22,1.79]		[0.11, 0.49]	[0.25, 1.82]
Median	0.29	0.97±1.75	0.62±1.28	1.20±2.00	0.030	0.71±1.51	1.36±2.06	0.006
		[0.11,68.00]	[0.09,.31.00]	[0.19,1.41]		[0.09, 0.33]	[0.22, 1.79]
Peak	0.69	2.46±3.85	0.92±1.50	3.46±4.6	0.007	1.86±3.17	3.36±4.67	0.074
		[0.29,2.61]	[0.16, 0.95]	[0.42,4.38]		[0.19, 1.68]	[0.47, 3.56]
24 h	0.20	0.82±1.47	0.59±1.13	0.98±1.65	0.053	0.73±1.67	0.97±1.11	0.017
		[0.09, 0.68]	[0.08,.36.00]	[0.15,1.12]		[0.09, 0.36]	[0.19, 1.67]
48 h	0.27	1.17±2.23	0.62±1.23	1.55±2.67	0.055	0.72±1.54	1.91±2.96	0.060
		[0.11, 0.74]	[0.09,.32.00]	[0.16,1.38]		[0.09, 0.31]	[0.24, 2.30]
72 h	0.27	1.37±2.90	0.54±1.24	1.95±3.57	0.080	0.70±1.52	2.78±4.42	0.020
		[0.11,1.08]	[0.09,.36.00]	[0.13,1.56]		[0.10, 0.38]	[0.26, 2.31]

IQR, interquartile range; SD, standard deviation; NSE, neuron specific enolase; MBP, myelin basic protein