Table 4.
Area under the curve for serum and clinical biomarkers to predict good vs. poor outcome and mortality at 6 months.
| 95% Confidence Interval | |||||
|---|---|---|---|---|---|
| Biomarker (outcome) | Area | Standard Error | p-value | Lower | Upper |
| NSE (good vs. poor) | 0.859 | 0.032 | <0.001 | 0.796 | 0.922 |
| NSE (mortality) | 0.787 | 0.033 | <0.001 | 0.721 | 0.852 |
| S100b (good vs. poor) | 0.955 | 0.017 | <0.001 | 0.922 | 0.987 |
| S100b (mortality) | 0.908 | 0.021 | <0.001 | 0.866 | 0.950 |
| MBP (good vs. poor) | 0.732 | 0.043 | <0.001 | 0.647 | 0.817 |
| MBP (mortality) | 0.727 | 0.037 | <0.001 | 0.654 | 0.799 |
| CPR-ROSC (good vs. poor) | 0.642 | 0.086 | 0.121 | 0.474 | 0.811 |
| CPR-ROSC (mortality) | 0.696 | 0.086 | 0.032 | 0.528 | 0.865 |
| First lactate (good vs. poor) | 0.749 | 0.074 | 0.006 | 0.604 | 0.893 |
| First lactate (mortality) | 0.809 | 0.079 | 0.001 | 0.654 | 0.964 |
| First blood pH (good vs. poor) | 0.752 | 0.074 | 0.006 | 0.608 | 0.896 |
| First blood pH (mortality) | 0.736 | 0.091 | 0.009 | 0.558 | 0.915 |
NSE, neuron specific enolase; MBP, myelin basic protein; CPR, cardiopulmonary resuscitation; ROSC, return of spontaneous circulation