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. Author manuscript; available in PMC: 2015 Jun 24.
Published in final edited form as: Crit Care Med. 2014 Mar;42(3):664–674. doi: 10.1097/01.ccm.0000435668.53188.80

Table 4.

Area under the curve for serum and clinical biomarkers to predict good vs. poor outcome and mortality at 6 months.

95% Confidence Interval
Biomarker (outcome) Area Standard Error p-value Lower Upper
NSE (good vs. poor) 0.859 0.032 <0.001 0.796 0.922
NSE (mortality) 0.787 0.033 <0.001 0.721 0.852
S100b (good vs. poor) 0.955 0.017 <0.001 0.922 0.987
S100b (mortality) 0.908 0.021 <0.001 0.866 0.950
MBP (good vs. poor) 0.732 0.043 <0.001 0.647 0.817
MBP (mortality) 0.727 0.037 <0.001 0.654 0.799
CPR-ROSC (good vs. poor) 0.642 0.086 0.121 0.474 0.811
CPR-ROSC (mortality) 0.696 0.086 0.032 0.528 0.865
First lactate (good vs. poor) 0.749 0.074 0.006 0.604 0.893
First lactate (mortality) 0.809 0.079 0.001 0.654 0.964
First blood pH (good vs. poor) 0.752 0.074 0.006 0.608 0.896
First blood pH (mortality) 0.736 0.091 0.009 0.558 0.915

NSE, neuron specific enolase; MBP, myelin basic protein; CPR, cardiopulmonary resuscitation; ROSC, return of spontaneous circulation