Table 1.
Drug treatments | Dose (mg/kg) | Paw volume (ml) | ||||
---|---|---|---|---|---|---|
1 h | 2 h | 3 h | 4 h | 5 h | ||
Saline | 0.09 ± 0.01 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | |
Saline + Carr | 0.47 ± 0.09 | 0.60 ± 0.12 | 0.37 ± 0.05 | 0.24 ± 0.04 | 0.19 ± 0.06 | |
Av-EtOH | 25 | 0.09 ± 0.05*** | 0.25 ± 0.05** | 0.36 ± 0.05 | 0.29 ± 0.07 | 0.20 ± 0.05 |
Av-EtOH | 50 | 0.16 ± 0.06** | 0.33 ± 0.06* | 0.22 ± 0.06 | 0.31 ± 0.06 | 0.28 ± 0.07 |
Av-EtOH | 100 | 0.12 ± 0.07*** | 0.17 ± 0.09*** | 0.22 ± 0.09 | 0.25 ± 0.09 | 0.17 ± 0.08 |
Indomethacin | 20 | 0.06 ± 0.03*** | 0.05 ± 0.02*** | 0.03 ± 0.02*** | 0.07 ± 0.03 | 0.03 ± 0.03 |
*P < 0.05; **P < 0.01; ***P < 0.001. Carr: carrageenan